Before the latest round of Premier League fixtures, here is all the key injury news alongside essential Fantasy Premier League statistics.

The gameweek is headlined by Arsenal's clash with Aston Villa which kicks off at 20:15 on Tuesday evening, and here are the fixtures in full.

This article will be updated as Premier League managers give their weekly news conferences.

For more FPL help, don't miss our regular Friday Q&A from 15:30 BST live on the BBC Sport website, with one of our four experts answering your questions

Tuesday

Burnley v Newcastle (19:30 GMT)

Burnley captain Josh Cullen is expected to miss out because of the knee issue that forced him off against Everton.

Defenders Maxime Esteve and Joe Worrall will be assessed and could return.

Newcastle head coach Eddie Howe does not expect to welcome back injured defenders Sven Botman, Dan Burn or Tino Livramento.

Players out: Burnley - Tuanzebe, Foster, Roberts, Mejbri, Beyer, Amdouni Newcastle - Osula, Botman, Elanga, Trippier, Krafth, Burn, Livramento

Doubts: Burnley - Cullen, Esteve, Worrall

Key FPL notes:

• Martin Dubravka (4.0m) kept his third clean sheet of the season against Everton in Gameweek 18, amassing 11 points.

• Anthony Gordon (£7.4m) has produced two double-digit hauls in the last four Gameweeks, thanks to one goal, two assists and four bonus points.

• Nick Woltemade (£7.4m) netted two goals against Chelsea in Gameweek 17, bringing his total for the season to seven - only four forwards have recorded more.

Chelsea v Bournemouth (19:30 GMT)

Chelsea defender Marc Cucurella could miss out because of the hamstring injury he suffered against Aston Villa.

The Blues also await news on the progress of Liam Delap and Estevao, who are recovering from shoulder and muscle injuries respectively.

Bournemouth's Alex Scott faces a fitness test having received a knock on his jaw - which he broke last season - during Saturday's game with Brentford.

Head coach Andoni Iraola is expected to make changes following their 4-1 defeat to the Bees.

David Brooks, Evanilson and Justin Kluivert could start after being introduced after half-time in that match.

Players out: Chelsea - Colwill, Hato, Lavia, Essugo, Mudryk Bournemouth - Gannon-Doak, Adams, Milosavljevic

Doubts: Chelsea - Delap, Estevao Bournemouth - Scott

Key FPL notes:

• Chelsea's Reece James (£5.7m) has played the full 90 minutes in each of the last four gameweeks. Across those matches, he has either scored, assisted or kept a clean sheet.

• Trevoh Chalobah (£5.5m) has amassed 24 points in his last four matches at Stamford Bridge, combining two clean sheets with a goal, two defensive contribution points and two bonus points.

• Antoine Semenyo (£7.7m) has scored in three consecutive matches. In Gameweek 18, only two players recorded more shots than the Bournemouth winger (five).

Nottingham Forest v Everton (19:30 GMT)

Nottingham Forest striker Chris Wood has had surgery on his troublesome knee injury and is set for a further spell on the sidelines.

Head coach Sean Dyche has no new injury concerns to deal with.

Everton's Jack Grealish had to sit out the draw with Burnley due to illness and will be assessed along with fellow midfielder Kiernan Dewsbury-Hall.

Iliman Ndiaye and Idrissa Gueye are at Afcon, while Jarrad Branthwaite and Seamus Coleman remain on the sidelines.

Players out: Nottingham Forest - Sangare, Boly, Aina, Wood, Yates Everton - Branthwaite, Coleman, Ndiaye, Gueye

Everton - Grealish, Dewsbury-Hall

Key FPL notes:

• With Chris Wood (£7.2m) expected to be out for several weeks following knee surgery, Igor Jesus (£5.8m) looks poised for further starts as Nottingham Forest's number nine. Since the start of November, the Brazilian has racked up 30 shots, the most of any forward except Erling Haaland (£15.1m).

• Nottingham Forest's John Victor (£4.0m) is emerging as a fresh budget goalkeeper of interest. Owned by only 0.4% of managers, he kept a clean sheet in Gameweek 16 and made three excellent saves against Manchester City last time out.

• Everton's Michael Keane (£4.8m) is the third-highest scoring defender in Fantasy, with 91 points. He produced his third double-digit haul of the campaign in Gameweek 18.

West Ham United v Brighton (19:30 GMT)

West Ham have no new injury worries to contend with following their defeat to Fulham.

They are without Aaron Wan-Bissaka and El Hadji Malick Diouf, who are both at the Africa Cup of Nations.

Brighton's Kaoru Mitoma returns having sat out the loss to Arsenal with illness.

Head coach Fabian Hurzeler says forward Danny Welbeck could be included in the starting line-up having been hampered by a back problem in recent weeks.

Players out: West Ham - Diouf, Fabianski, Fullkrug, Wan-Bissaka Brighton - Baleba, March, Tzimas, Webster

Key FPL notes:

• West Ham's Jarrod Bowen (£7.6m) has produced two goals and an assist in the last five gameweeks. During that period, only two forwards have recorded more shots (14).

• No defender has scored more goals than Brighton's Jan Paul van Hecke's (£4.5m) two since Gameweek 10, while only four have kept more clean sheets than his four.

• Only five midfielders have had more big chances (three) than Brighton's Georginio Rutter (£5.6m) over the last four gameweeks.

Arsenal v Aston Villa (20:15 GMT)

Arsenal await news on whether defenders Riccardo Calafiori and Jurrien Timber have recovered from the injuries that ruled them out of the win over Brighton.

Gabriel came off the bench in that game for his first appearance since early November and could start, while Kai Havertz is also close to a return.

Aston Villa are without Matty Cash and Boubacar Kamara because of suspension after they both received a fifth yellow card of the season against Chelsea on Saturday.

Players out: Arsenal - Mosquera, White, Dowman Aston Villa - Barkley, Cash, Guessand, Kamara, Mings, Torres

Doubts: Arsenal - Calafiori, Havertz, Timber

Key FPL notes:

• No player had more shots than Bukayo Saka's (£10.3m) seven in Gameweek 18, while only two created more chances (four) than the Arsenal forward.

• Martin Odegaard (£7.8m) created five chances in Gameweek 18, the joint-most of any player. The Gunners midfielder also scored his first goal of the campaign against Brighton and Hove Albion.

• Aston Villa's Ollie Watkins (£8.5m) has produced four goals and two assists in the last five gameweeks, amassing 37 points.

Manchester United v Wolves (20:15 GMT)

Manchester United midfielder Mason Mount faces a fitness test on the injury that forced him off against Newcastle.

Bruno Fernandes, Kobbie Mainoo, Matthijs de Ligt and Harry Maguire will again miss out, while Amad Diallo, Noussair Mazraoui and Bryan Mbeumo are at the Africa Cup of Nations.

Wolves are without midfielder Andre, who serves a one-match suspension following his fifth booking of the season.

Yerson Mosquera should be fit after suffering from cramp against Liverpool, but Santiago Bueno is a doubt with a knock.

Players out: Man Utd - De Ligt, Fernandes, Mainoo, Maguire, Mbeumo, Amad Diallo, Mazraoui Wolves - Agbadou, Andre, Bellegarde, Chirewa, Chiwome, Munetsi, R Gomes, Toti

Doubts: Man Utd - Mount Wolves - Bueno

Key FPL notes:

• Not only has Matheus Cunha (£8.1m) registered at least eight more shots than any other player over the last four gameweeks (25), but the Manchester United forward also has attacking returns in three of his last four matches.

• United wing-back Patrick Dorgu (£4.1m) was the second-highest scoring player of Gameweek 18, with 17 points.

• Tolu Arokodare (£5.4m) has been Wolves' highest-scoring player over the last three gameweeks (13 points), thanks to one goal, one assist and two bonus points.

Thursday

Crystal Palace v Fulham (17:30 GMT)

Crystal Palace defender Chris Richards could again be absent because of the foot injury that caused him to miss the defeat to Spurs on Sunday.

Fulham are still without Calvin Bassey, Samuel Chukwueze and Alex Iwobi, all of whom are at Afcon with Nigeria.

Players out: Crystal Palace - Sarr, Kamada, Munoz, Doucoure Fulham - Bassey, Chukwueze, Iwobi, Muniz, Sessegnon

Doubts: Crystal Palace - Richards

Key FPL notes:

• Only one midfielder has had more big chances (three) over the last two gameweeks than Crystal Palace's Justin Devenny (£4.3m).

• Fulham's Harry Wilson (£5.8m) has served up 49 points across his previous six matches and continues to offer excellent value in Fantasy.

• Raul Jimenez (£6.3m) has scored four goals this season, with two arriving in the last two gameweeks. During that period, the Cottagers forward has racked up 10 shots, the most of any player except Bukayo Saka.

Liverpool v Leeds United (17:30 GMT)

Liverpool midfielder Dominik Szoboszlai is available again having sat out the win over Wolves due to suspension.

Leeds defender Joe Rodon suffered an ankle injury against Sunderland that could bring to an end his two-year streak of consecutive league appearances.

Players out: Liverpool - Isak, Gomez, Endo, Salah, Leoni Leeds - James, Longstaff

Doubts: Leeds - Rodon

Key FPL notes:

• Ryan Gravenberch (£5.7m) is Liverpool's top-scoring player this season, producing 84 points thanks to four goals, three assists, eight defensive contribution points and 13 bonus.

• Dominik Szoboszlai (£6.6m) ranks first among Liverpool players for shots and key passes combined since the start of November, with a total of 33.

• Dominic Calvert-Lewin (£5.8m) scored his seventh goal in six matches to pull Leeds United level at Sunderland on Sunday.

Brentford v Tottenham (20:00 GMT)

Brentford defender Sepp van den Berg missed the win over Bournemouth after picking up a knock and will be assessed.

Tottenham captain Cristian Romero returns from suspension, but Xavi Simons serves the second game of his three-match ban.

Players out: Brentford - Carvalho, Dasilva, Milambo, Onyeka, Ouattara Tottenham - Kulusevski, Maddison, Sarr, Simons, Solanke, Udogie, Bissouma

Doubts: Brentford - Van den Berg

Key FPL notes:

• Brentford's Igor Thiago (£7.0m) produced an assist against Bournemouth in Gameweek 18, but really should have had one of his own, missing a big chance in the first half.

• Bees midfielder Mikkel Damsgaard (£5.8m) has provided assists in back-to-back matches, amassing eight points.

• Tottenham defender Micky van de Ven (£4.5m) recorded his first double-digit haul since Gameweek 9 on Sunday, thanks to a clean sheet, the maximum bonus and defensive contribution points.

Sunderland v Man City (20:00 GMT)

Sunderland defender Dan Ballard is a doubt after being ruled out of their match against Leeds on Sunday with an ankle injury.

Luke O'Nien returns to the squad having served a three-match ban following his red card in the reverse fixture in early December.

Manchester City await news on which of their injured players will be available for this fixture.

Jeremy Doku and John Stones are among those who will be assessed.

Players out: Sunderland - Diarra, O'Nien, Traore, Talbi, Reinildo, Sadiki, Masuaku, Alese Man City - Ait-Nouri, Bobb, Kovacic, Marmoush, Rodri, Stones

Doubts: Sunderland - Ballard Man City - Doku, Stones

Key FPL notes:

• Sunderland's Omar Alderete (£4.0m) has banked defensive contribution points in six of his past 12 matches.

• Tijjani Reijnders (£5.2m) found the net for Manchester City in Gameweek 18 and has now scored three goals in his last five matches, which notably included four starts.

• Man City's Rayan Cherki (£6.7m) has produced nine attacking returns since the start of November, the joint-most of any player except Erling Haaland.