A puppy found abandoned in grueling conditions at a Florida park has died, despite efforts by rescuers to save him.

Frosty, a purebred Shiba Inu, was rescued two days after nine puppies and their two moms were left inside a plastic storage bin at Taylor Park in Largo on December 19.

All of the dogs were suffering from parvovirus, a highly contagious and sometimes fatal disease.

Frosty was placed in the care of the Pawlicious Poochie Pet Rescue, which confirmed his passing on Wednesday morning following more than a week of treatment.

'The world's bravest little boy lost his fight late last night in my arms,' a statement said. 'We are all emotionally and physically defeated and exhausted.'

A necropsy revealed a 'huge hole' Frosty's small intestines, consistent with his 'clean snap break' of his back leg and dislocated jaw.

He died 'from the physical trauma he suffered' before being rescued, the statement concluded.

Frosty, a purebred Shiba Inu, died after being rescued from Taylor Park in Largo earlier this month

Jaime McKnight, the founder of the pet rescue, called Frosty's abandonment 'disgusting' and 'cruel.'

She said she was initially contacted by Largo police with news of the deserted dogs.

'Had they not been found when they did, I think we would have been looking at a different situation,' McKnight told WTSP.

However, Frosty's treatment was delayed for about two days until he was also rescued.

'That one [was] struggling a little bit more,' Dr. Jeff Cartzendafener, of the Skyway Animal Hospital, said.

He added: 'It's very sad to think someone could just leave sick puppies in a park somewhere to kind of fend for themselves.'

Both were present during Frosty's final moments, according to a Facebook post on Wednesday morning.

Frosty was rescued just two days after nine other puppies and their two moms were abandoned inside a plastic storage bin at the park

Frosty's necropsy showed a 'huge hole' in his small intestines, along with a 'clean snap break' of his back leg (pictured) and a dislocated jaw

'Dr. C checked him out and I continued to carry him around and tell him he was going to be ok like I always do,' McKnight wrote.

'He knew I was there and then just like that as I held him with Dr.C he took his last breathes [sic] and was gone,' she added. 'Quietly, peacefully and in my arms.'

The pet rescue had previously described Frosty's condition as 'super critical', adding that their concern went beyond the canine parvovirus.

McKnight posted: 'It's the direct result of his physical injuries. The back leg that's snapped in half and the dislocated jaw.'

Heartbreaking footage posted by the rescue showed Frosty receiving gentle pets as he received treatment and desperately clung on to his life.